Auguste Deter
Alois Alzheimer records his first examination of Auguste Deter
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Original prompt & settings (JSON) ↗On her second day in the asylum, Deter told Alzheimer she had already been there three weeks.
Admitted on the 25th, examined on the 26th
Auguste Deter, aged 51, was admitted to Frankfurt's municipal asylum on 25 November 1901, but Alzheimer's surviving examination notes begin on 26 November. That is the better-supported date for their documented first interview, and later biographies often collapse the two.
Alzheimer systematically tested her identity, orientation, memory and ability to name objects. She gave "Auguste" as both her first and last names, and thought her husband might be named Auguste as well.
Pork, cauliflower, spinach
Although it was only her second day in the institution, Deter answered that she had been there for three weeks.
She called a pencil a pen and correctly identified several other objects. At lunch she was eating pork and cauliflower, and called it spinach.
The examinations continued on 28, 29 and 30 November, with her answers and samples of her writing recorded; the often-quoted line "I have lost myself" belongs to the entry of 29 November.
No disease was diagnosed
There was as yet nothing called Alzheimer's disease to diagnose. The clinicopathological description followed Deter's death in 1906, and Kraepelin introduced the eponym in his 1910 textbook.
The decisive observations — plaques and neurofibrillary tangles — could not be made during an interview; they came from postmortem tissue. Deter was the first published index case of the condition, not the first person ever to have it.
The original clinical file was rediscovered in Frankfurt in the 1990s, which is why the exact wording and dates of these examinations are available again.
Sources
Researched 24 Aug 2026 6 sources not yet audited Date disputed
How this was checked
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Date disputed. Sources disagree; the research places it at 1901-11-26.
What the sources leave uncertain
- The listed date, 25 November, is securely supported as Deter’s admission date, but the rediscovered case file says Alzheimer’s notes begin on 26 November. Some later biographies collapse admission and first examination into the 25th. Sources: https://www.amherst.edu/media/view/294178/original/AD_Maurer%201997.pdf and https://pmc.ncbi.nlm.nih.gov/articles/PMC8095522/
- Calling the encounter a diagnosis of 'Alzheimer’s disease' is anachronistic. The clinicopathological description followed Deter’s death in 1906; Kraepelin introduced the eponym in his 1910 textbook. Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC3181715/
Checked against
- Auguste D and Alzheimer’s disease — The Lancet
- A labyrinth of tangles: Alzheimer’s disease — Cambridge University Press
- Alois Alzheimer: His Life and Times
- The discovery of Alzheimer’s disease
- About a Peculiar Disease of the Cerebral Cortex: Alzheimer’s Original Case Revisited
- Histopathology and APOE genotype of the first Alzheimer disease patient, Auguste D.